What is Lung Cancer? Lung cancer is a malignant growth that begins in the spongy, oxygen-exchanging organs in your chest. It occurs when cells in the lungs mutate and multiply uncontrollably, forming tumors that interfere with your ability to breathe. Key Fact: Lung cancer remains the leading cause of cancer-related deaths worldwide for both men and women. However, massive advancements in targeted therapies , immunotherapy , and early low-dose CT screening are steadily and significantly improving survival rates. Signs & Symptoms Lung cancer typically does not present noticeable signs or symptoms in its earliest, most curable stages. As the disease progresses, common symptoms may include: A New, Persistent Cough: A cough that does not go away after 2–3 weeks or progressively worsens. Changes in a Chronic "Smoker's Cough": Noticing a deeper sound, a change in frequency, or an increase in mucus ...