What is Alcohol Use Disorder (Alcoholism)? Alcoholism, clinically diagnosed as Alcohol Use Disorder (AUD), is a chronic, relapsing brain disease characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences. It involves both profound psychological compulsion and physical dependence, meaning your body eventually requires increasing amounts of alcohol to achieve the same effect (tolerance) and experiences dangerous physical withdrawal symptoms when you attempt to stop. It is entirely possible to be a "problem drinker" without being fully physically dependent. However, chronic binge drinking and heavy use can rapidly progress to severe AUD. Denial is a hallmark symptom of this disorder; consequently, many people cannot safely quit without professional medical intervention. Symptoms The clinical signs of Alcohol Use Disorder exist on a spectrum from mild ...