What is Rheumatoid Arthritis (RA)? Rheumatoid arthritis is a chronic inflammatory autoimmune disorder. Unlike the standard "wear-and-tear" arthritis (osteoarthritis) that happens as we age, RA occurs when your immune system mistakenly identifies the lining of your own joints (the synovium) as a threat and attacks it. Systemic Impact: RA is not restricted to the joints. Because it is a systemic immune issue, severe or untreated cases can cause widespread inflammation that damages the skin, eyes, lungs, heart, and blood vessels. RA vs. Osteoarthritis: Knowing the Difference Understanding whether your joint pain is autoimmune or mechanical is the first step toward effective treatment. Feature Rheumatoid Arthritis (Autoimmune) Osteoarthritis (Wear & Tear) Morning Stiffness Lasts for more than an hour ; often r...