What is an Enlarged Liver? The clinical medical term for an enlarged liver is Hepatomegaly . It means that the liver has swollen to a size larger than normal. An enlarged liver is not a disease in and of itself; rather, it is a significant physical warning sign of an underlying medical problem, such as chronic liver disease, congestive heart failure, or certain types of cancer. The liver is a large, football-shaped organ located in the upper right portion of your abdomen, tucked mostly beneath your rib cage. Because it is essential for filtering toxins and digesting fats, treatment must focus on identifying and controlling whatever is causing the swelling. Symptoms In mild cases, an enlarged liver may not cause any noticeable symptoms at all. However, as the swelling increases or the underlying liver disease progresses, you may experience: A feeling of fullness, heaviness, or dull aching pain in the upper right side...